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ea0049gp182 | Pituitary | ECE2017

Brain white matter damage and volumes of hippocampus and hypothalamus correlates to cognitive function in craniopharyngioma

Fjalldal Sigridur , Svard Daniel , Follin Cecilia , Westen Danielle Van , Gabery Sanaz , Petersen AEsa , Jansson Magdalena , Sundgren Pia Maly , Bjorkman-Burtscher Isabella , Latt Jimmy , Mannfolk Peter , Nordstrom Carl-Henrik , Rylander Lars , Ekman Bertil , Johansson Aki , Erfurth Eva-Marie

Introduction: Adult patients with craniopharyngioma (CP) and hypothalamic (HT) damage have impaired cognitive function. The white matter (WM) changes behind these findings remain to be elucidated. Diffusion tensor imaging (DTI) is a MRI technique that quantifies microstructural damage in the WM. This is the first study of DTI, hippocampal (HC) and HT volume in relation to cognition in CP patients.Methods: A cross-sectional study of childhood onset CP was...

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Brain white matter damage and volumes of hippocampus and hypothalamus correlates to cognitive function in craniopharyngioma

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